The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2023

Filed:

Dec. 07, 2020
Applicant:

General Electric Company, Schenectady, NY (US);

Inventors:

Jessica Godin Karp, Schenectady, NY (US);

Xiaohui Chen, Schenectady, NY (US);

Kashan Ali Shaikh, Clifton Park, NY (US);

Mengli Wang, Rexford, NY (US);

Ralf Lenigk, Schenectady, NY (US);

Christine Lynne Surrette, Albany, NY (US);

Assignee:

General Electric Company, Schenectady, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/49 (2006.01); B01L 3/00 (2006.01); C12Q 1/24 (2006.01); G01N 1/40 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5002 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); B01L 3/502761 (2013.01); B01L 3/502769 (2013.01); C12Q 1/24 (2013.01); G01N 33/491 (2013.01); B01D 2313/18 (2013.01); B01D 2313/50 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/16 (2013.01); G01N 2001/4088 (2013.01);
Abstract

A device and/or methodology are described that include a mechanism for separating erythrocytes from other constituents of blood and for purifying leukocytes from blood. The separation and purification aspects may be provided in separate components or within the same component. The separation aspect assists in separating erythrocytes (red blood cells) from other cells in blood, such as by aggregation of the red blood cells. A suitable aggregation device or device component uses chambers with at least one small dimension (e.g., a microfluidic chip) to control the interaction of the blood with a solution containing a high molecular weight polymer (e.g., dextran) to achieve separation.


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