The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2023
Filed:
Sep. 18, 2017
Applicant:
Koligo Therapeutics, Inc., New Albany, IN (US);
Inventors:
Rolf Wolters, Kailua, HI (US);
Anthony Yang, Honolulu, HI (US);
Josh Nelson, Kaleohe, HI (US);
Stuart K. Williams, Harrods Creek, KY (US);
Assignee:
TISSUE GENESIS INTERNATIONAL LLC, Leander, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); B01L 3/00 (2006.01); A61M 1/00 (2006.01); G01N 1/34 (2006.01); C12N 5/077 (2010.01); G01N 1/40 (2006.01); C12N 5/0775 (2010.01); A61K 35/35 (2015.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
G01N 1/34 (2013.01); A61K 35/35 (2013.01); A61M 1/79 (2021.05); C12M 41/00 (2013.01); C12N 5/0653 (2013.01); C12N 5/0667 (2013.01); G01N 1/4044 (2013.01); A61M 1/73 (2021.05); A61M 2202/0014 (2013.01); A61M 2202/0071 (2013.01); A61M 2202/0085 (2013.01); A61M 2202/08 (2013.01); A61M 2202/09 (2013.01); C12N 2509/10 (2013.01);
Abstract
Systems and methods herein are directed towards the separation of biologic material to obtain a target cell volume and/or cell concentration for harvesting. The target volume and/or concentration of cells may be obtained through a single cycle via three chambers, or by repeated cycles through one or more chambers to dilute the digestive enzymes used in the process and concentrate the harvestable cell volume to a predetermined target.