The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2023

Filed:

Mar. 31, 2017
Applicant:

Nanomed Diagnostics B.v., Enschede, NL;

Inventors:

Willem Frederik Rurup, Best, NL;

Loes Irene Segerink, Enschede, NL;

Roderik Adriaan Kraaijenhagen, Amstelveen, NL;

Herbert Michael Pinedo, Amsterdam, NL;

Albert Van Den Berg, Nijverdal, NL;

Renske Daniëla Maria Steenbergen, Enschede, NL;

Jacobus Adrianus Nieuwenhuijzen, Amsterdam, NL;

Idris Bahce, Enschede, NL;

Geert Kazemier, Enschede, NL;

Assignee:

Nanomed Diagnostics BV, Enschede, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/686 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01);
Abstract

The invention provides in vitro methods of determining whether an individual has a pre-cancer or cancer comprising determining the presence or absence of one or more methylation markers of a methylation marker set in a urine sample of said individual; and determining whether the individual has pre-cancer or cancer based on the detection of the presence or absence of said one or more methylation markers in the urine sample, wherein the presence of said one or more methylation markers indicates that the individual has pre-cancer or cancer. The invention further provides methods for typing pre-cancer or cancer based on the the presence or absence of one or more methylation markers of a methylation marker set in a urine sample.


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