The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2023

Filed:

Feb. 27, 2020
Applicant:

The Scripps Research Institute, La Jolla, CA (US);

Inventors:

Daniel R. Salomon, San Diego, CA (US);

Sunil M. Kurian, San Diego, CA (US);

Steven R. Head, San Diego, CA (US);

Assignee:

THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01);
Abstract

By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with chronic allograft nephropathy and/or interstitial fibrosis and tubular atrophy CAN/IFTA and subtypes thereof. These genes sets are useful for diagnosis, prognosis, monitoring and/or subtyping of CAN/IFTA.


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