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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11821012 B1

PDFFull Text
Date of Patent:
Nov. 21, 2023

Filed:

Nov. 04, 2022

Gene editing systems comprising an rna guide targeting hydroxyacid oxidase 1 (hao1) and uses thereof

Applicant:

Arbor Biotechnologies, Inc., Cambridge, MA (US);

Inventors:

Quinton Norman Wessells, Cambridge, MA (US);

Jeffrey Raymond Haswell, Needham, MA (US);

Tia Marie Ditommaso, Newton, MA (US);

Noah Michael Jakimo, San Francisco, CA (US);

Sejuti Sengupta, Ashland, MA (US);

Assignee:

Arbor Biotechnologies, Inc., Cambridge, MA (US);

Attorney:

McDermott, Will & Emery LLP

Primary Examiner:

Allison M Fox

Assistant Examiner:

Kimberly A Aron

Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61P 13/12 (2006.01); A61K 31/7105 (2006.01); A61K 38/16 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01); A61K 48/00 (2006.01); A61K 38/46 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 31/7105 (2013.01); A61K 38/465 (2013.01); A61P 13/12 (2018.01); C12N 15/11 (2013.01); C12N 15/86 (2013.01); C12N 15/907 (2013.01); A61K 48/00 (2013.01); C12N 2310/20 (2017.05); C12N 2750/14143 (2013.01); C12N 2800/80 (2013.01);
Abstract

Provided herein are gene editing systems and/or compositions comprising RNA guides targeting HAO1 for use in genetic editing of the HAO1 gene. Also provide herein are methods of using the gene editing system for introducing edits to the HAO1 gene and/or for treatment of primary hyperoxaluria (PH), and processes for characterizing the gene editing system.

Find Patent Forward Citations

Wessells, Quinton. (2023). Gene editing systems comprising an rna guide targeting hydroxyacid oxidase 1 (hao1) and uses thereof (U.S. Patent No. 11821012). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11821012

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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