The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2023
Filed:
Nov. 02, 2020
Applicant:
Mesoblast International Sárl, Meyrin, CH;
Inventors:
Alla Danilkovitch, Columbia, MD (US);
Diane Carter, Huntington, MD (US);
Alicia Mildred Tyrell, Cantonsville, MD (US);
Simon Bubnic, Ann Arbor, MI (US);
Michelle Marcelino, IJamsville, MD (US);
Rodney Monroy, Aberdeen, MD (US);
Assignee:
MESOBLAST INTERNATIONAL SÁRL, Meryin, CH;
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2020.01); G01N 33/53 (2006.01); C12N 5/00 (2006.01); C12N 5/0775 (2010.01); A61K 35/28 (2015.01); A01K 67/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0662 (2013.01); A61K 35/28 (2013.01); C12N 5/0663 (2013.01); A61K 2035/122 (2013.01); C12N 2501/25 (2013.01); G01N 2333/525 (2013.01);
Abstract
Mesenchymal stem cells which express TNF-α receptor Type I in an amount of at least 13 pg/10cells. Such mesenchymal stem cells inhibit the proliferation of lymphocytes and may be employed, in particular, in the treatment of graft-versus-host disease.