The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2023

Filed:

Jul. 17, 2020
Applicants:

Gemini Therapeutics Sub, Inc., Cambridge, MA (US);

Stichting Sanquin Bloedvoorziening, Amsterdam, NL;

Inventors:

Scott Lauder, Somerville, MA (US);

Tom Purcell, Mountain View, CA (US);

Sridhar Govindarajan, Los Altos, CA (US);

Taco Willem Kuijpers, Amsterdam, NL;

Diana Wouters, Badhoevedorp, NL;

Maria Clara Brouwer, Blokker, NL;

Richard Benjamin Pouw, Amsterdam, NL;

Taede Rispens, Utrecht, NL;

Ilse Jongerius, De Bilt, NL;

Gillian Dekkers, Utrecht, NL;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 47/60 (2017.08); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Provided herein are novel isolated, synthetic or recombinant antibodies and fragments thereof specific for factor H, or nucleic acids or vectors encoding such antibodies and fragments. Further provided herein is the use of such antibodies, fragments, nucleic acids or vectors for inhibiting complement activation and treatment of disorders associated with complement activation.


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