The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2023
Filed:
Sep. 05, 2017
Applicant:
Cytiva Bioprocess R&d Ab, Uppsala, SE;
Inventors:
Assignee:
Cytiva BioProcess R&D AB, Uppsala, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 1/22 (2006.01); C07K 14/31 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4728 (2013.01); C07K 1/22 (2013.01); C07K 14/31 (2013.01); C07K 2319/20 (2013.01); C07K 2319/30 (2013.01); C07K 2319/705 (2013.01);
Abstract
The present invention is within the field of protein engineering and purification. The invention relates to a target-binding polypeptide mutant of an IgG binding polypeptide, such as Protein A, Protein G, Protein L or Protein M, comprising a metal binding motif. More closely the invention relates to an Fc binding ligand comprising an engineered protein based on the Protein A derived Z domain, to which a calcium binding EF-loop has been introduced.