The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2023
Filed:
May. 24, 2021
Watson Laboratories Inc., Corona, CA (US);
Dolitzky Ben-Zion, Petach Tikva, IL;
Mendelovici Marioara, Rehovot, IL;
Bodkhe Arjun Rajaram, Thane, IN;
Mane Ganesh Shivaji, Thane, IN;
Samala Rajamouli Srihari, Thane, IN;
Joshi Ashutosh Vijay, Thane, IN;
Parven Kumar Luthra, New Delhi, IN;
Amit Singh, Greater Noida, IN;
Anantha Rajmohan Muthusamy, Sivakasi, IN;
ASSIA CHEMICAL INDUSTRIES LTD., Tel Aviv, IL;
Abstract
The present disclosure relates to novel processes for the preparation of short acting benzodiazepines as well as to novel intermediates in this process. More particularly the disclosure relates to processes and intermediates for preparation of Methyl 3-[(4S)-8-bromo-1-methyl-6-(pyridin-2-yl)-4H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propanoate, commonly known as Remimazolam. The present disclosure also relates to solid state forms of Remimazolam salts, processes for the preparation thereof, pharmaceutical formulations/compositions thereof, and methods of use thereof.