The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2023

Filed:

Jul. 14, 2021
Applicant:

Lead High Technology (Qingdao) Co., Ltd, Shandong, CN;

Inventors:

Dayong Shi, Qingdao, CN;

Xiangqian Li, Qingdao, CN;

Xin Wang, Qingdao, CN;

Jinbo Yang, Qingdao, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/06 (2006.01); C07D 417/04 (2006.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); A61P 31/14 (2018.01); C07D 231/06 (2013.01);
Abstract

The present invention relates to a compound, and in particular to a bromophenol-pyrazoline compound and a synthesis method and use thereof. The bromophenol-pyrazoline compound is represented by a general structural formula below: The bromophenol-pyrazoline compound provided in the present invention has efficient inhibitory activity against the main protease M, and interferes with the replication of coronavirus in cells, indicating that the compound has the effect of treating coronavirus pneumonia and thus has a broad prospect of application in the preparation of drugs for treating coronavirus pneumonia.


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