The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2023
Filed:
Feb. 10, 2021
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Robert Todd Striker, Madison, WI (US);
Nathan Joseph Wlodarchak, Madison, WI (US);
John Bruce Feltenberger, Madison, WI (US);
Jennifer Golden, Waunakee, WI (US);
Assignees:
Wisconsin Alumni Research Foundation, Madison, WI (US);
U.S. Dept. of Veterans Affairs, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 239/42 (2006.01); C07D 417/04 (2006.01); C07D 277/28 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); A61K 31/496 (2006.01); A61P 31/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); A61P 31/06 (2018.01); C07D 239/42 (2013.01); C07D 277/28 (2013.01); C07D 417/04 (2013.01);
Abstract
Biochemically active PASTA kinase inhibitors which exploit subtle structural differences between human kinases and bacterial PASTA kinases to improve specificity and inhibitor activity. The disclosed kinase inhibitors have the general formula: wherein: