The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2023
Filed:
Nov. 04, 2016
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Fei Wen, Ann Arbor, MI (US);
Mason Smith, Ann Arbor, MI (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/62 (2006.01); C12N 5/0783 (2010.01); C07K 14/39 (2006.01); A61K 35/17 (2015.01); A61K 48/00 (2006.01); A61K 47/61 (2017.01); A61K 47/68 (2017.01); A61K 38/17 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 38/1774 (2013.01); A61K 47/61 (2017.08); A61K 47/6889 (2017.08); A61K 48/00 (2013.01); C07K 14/39 (2013.01); C07K 19/00 (2013.01); C12N 5/0636 (2013.01); C12N 15/62 (2013.01); C07K 2318/10 (2013.01); C07K 2319/02 (2013.01); C07K 2319/035 (2013.01);
Abstract
Provided herein is technology relating to immunotherapy and particularly, but not exclusively, to compositions, methods, and kits for immunotherapy and activation of T cells using a peptide-major histocompatibility complex (pMHC) assembled on a protein scaffold for patterned signal presentation of T cell activating ligands to T cells.