The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2023

Filed:

Aug. 04, 2020
Applicant:

Radius Pharmaceuticals, Inc., Boston, MA (US);

Inventors:

Fiona Garner, Boston, MA (US);

Gary Hattersley, Stow, MA (US);

Assignee:

RADIUS PHARMACEUTICALS, INC., Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/137 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61K 31/436 (2006.01); A61K 31/675 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 31/436 (2013.01); A61K 31/519 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01); A61K 2300/00 (2013.01);
Abstract

Disclosed herein are methods of inhibiting tumor growth or producing tumor regression in a subject having a drug-resistant estrogen receptor alpha positive cancer or a mutant estrogen receptor alpha positive cancer. The methods entail administering to the subject a therapeutically effective amount of RAD1901 having the structure: or a salt or solvate thereof.


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