The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2023

Filed:

Apr. 25, 2022
Applicants:

Vib Vzw, Ghent, BE;

Katholieke Universiteit Leuven, K.u. Leuven R&d, Leuven, BE;

Life Sciences Research Partners Vzw, Leuven, BE;

Inventors:

Diether Lambrechts, Kessel-Lo, BE;

Bernard Thienpont, Jette, BE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 2600/154 (2013.01);
Abstract

The present application relates to the field of cancer, particular to hypoxic tumors. It was found that hypoxia is an important driver for hypermethylation of (promoters of) tumor suppressor genes. As this hypermethylation is a stable signature that is also present in circulating tumor DNA in peripheral blood, detecting this methylation pattern is a surrogate marker for tumor hypoxia. This can be used to adapt therapy as well.


Find Patent Forward Citations

Lambrechts, Diether. (2023). Markers for determining tumor hypoxia (U.S. Patent No. 11814688). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11814688

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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