The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2023

Filed:

Mar. 29, 2021
Applicant:

Celera Corporation, San Juan Capistrano, CA (US);

Inventors:

Olga Iakoubova, San Ramon, CA (US);

James J. Devlin, Lafayette, CA (US);

Carmen Tong, Dublin, CA (US);

Charles Rowland, San Leandro, CA (US);

Assignee:

Celera Corporation, San Juan Capistrano, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01); C12Q 2600/172 (2013.01); G01N 2333/914 (2013.01); G01N 2500/04 (2013.01); G01N 2800/32 (2013.01); G01N 2800/324 (2013.01); G01N 2800/329 (2013.01); Y10T 436/143333 (2015.01);
Abstract

The present invention provides compositions and methods based on genetic polymorphisms that are associated with coronary heart disease (particularly myocardial infarction), aneurysm/dissection, and/or response to drug treatment, particularly statin treatment. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.


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