The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2023
Filed:
Sep. 20, 2018
Applicants:
The University of British Columbia, Vancouver, CA;
Sangamo Therapeutics France, Valbonne Sophia Antipolis, FR;
Inventors:
Li Zhou, West Roxbury, MA (US);
Tobias Abel, Antibes, FR;
François Meyer, Porrentruy, CH;
Megan Levings, Vancouver, CA;
Nicolas Dawson, Vancouver, CA;
Caroline Lamarche, Vancouver, CA;
Assignees:
The University of British Columbia, Vancouver, CA;
Sangamo Therapeutics France, Valbonne Sophia Antipolis, FR;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 35/17 (2015.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C07K 16/2833 (2013.01); A61K 35/17 (2013.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70575 (2013.01); A61K 2035/122 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/622 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01);
Abstract
The present invention relates to a novel anti-HLA-A2 antibody, and to a chimeric antigen receptor comprising said HLA-A2 antibody. The present invention further relates to an immune cell expressing said chimeric receptor antigen, and to therapeutic uses thereof, in particular for treating or preventing graft rejection or GVHD.