The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2023
Filed:
Nov. 02, 2018
Cytomx Therapeutics, Inc., South San Francisco, CA (US);
Stephen James Moore, Danville, CA (US);
Margaret Thy Luu Nguyen, San Francisco, CA (US);
Daniel R. Hostetter, Rocklin, CA (US);
Olga Vasiljeva, Cupertino, CA (US);
Jeanne Grace Flandez, Oakland, CA (US);
CYTOMX THERAPEUTICS, INC., South San Francisco, CA (US);
Abstract
The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one matrix metalloprotease (MMP), to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one MMP protease, and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one MMP protease in a variety of therapeutic, diagnostic and prophylactic indications.