The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2023
Filed:
Jan. 25, 2019
Applicant:
Hoffmann-la Roche Inc., Nutley, NJ (US);
Inventors:
Roberto Falkenstein, Munich, DE;
Hubert Hertenberger, Weilheim, DE;
Petra Rueger, Penzberg, DE;
Tilman Schlothauer, Penzberg, DE;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); B01D 15/16 (2006.01); B01D 15/38 (2006.01); B01J 20/289 (2006.01); B01J 20/32 (2006.01); C07K 16/06 (2006.01); C07K 16/28 (2006.01); B01J 39/26 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); B01D 15/168 (2013.01); B01D 15/3809 (2013.01); B01J 20/289 (2013.01); B01J 20/3204 (2013.01); B01J 20/3206 (2013.01); B01J 20/3219 (2013.01); B01J 20/3274 (2013.01); B01J 39/26 (2013.01); C07K 16/065 (2013.01); C07K 16/2866 (2013.01); G01N 33/6854 (2013.01);
Abstract
Herein is reported the use of an immobilized non-covalent complex of a neonatal Fc receptor (FcRn) and beta-2-microglobulin (b2m) as affinity chromatography ligand in general and, for example, for the determination of the in vivo half-live of an antibody by determining the ratio of the retention times of the antibody and a reference antibody.