The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2023
Filed:
Mar. 14, 2022
Maze Therapeutics, Inc., South San Francisco, CA (US);
David John Morgans, Jr., Los Altos, CA (US);
Kevin Mellem, Redwood City, CA (US);
Hannah L. Powers, San Diego, CA (US);
Patrick Sang Tae Lee, Walnut Creek, CA (US);
Walter Won, San Diego, CA (US);
Christopher Joseph Sinz, Walnut Creek, CA (US);
MAZE THERAPEUTICS, INC., South San Francisco, CA (US);
Abstract
Provided herein are compounds of formula (I'): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein Y, Y, L, L, X, X, X, X, X, Q, R, R, R, R, and Rare as defined elsewhere herein. Also provided herein are methods of preparing compounds of formula (I′). Also provided herein are methods of inhibiting GYS1 and methods of treating a GYS1-mediated disease, disorder, or condition in an individual in need thereof.