The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2023

Filed:

Mar. 17, 2022
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Guozhang Xu, Chesterbrook, PA (US);

Boying Guo, Glenside, PA (US);

Zhijie Liu, Paoli, PA (US);

Jing Zhang, Wilmington, DE (US);

Micheal D. Gaul, Apex, NC (US);

Eugene B. Grant, Flemington, NJ (US);

Mark J. Macielag, Gwynedd Valley, PA (US);

Tianbao Lu, Churchville, PA (US);

Tho V. Thieu, North Wales, PA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 417/14 (2006.01); C07D 413/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention is directed to pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.


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