The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2023
Filed:
Jan. 28, 2021
The Regents of the University of Michigan, Ann Arbor, MI (US);
The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);
Zhen Xu, Ann Arbor, MI (US);
Clifford Suhyun Cho, Ann Arbor, MI (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
The United States Government as represented by the Department of Veterans Affairs, Washington, DC (US);
Abstract
Systems and methods for histotripsy and immunotherapy are provided. In some embodiments, histotripsy can be applied to a target tissue volume to lyse and solubilize the target tissue volume to release tumor antigens. In some embodiments, an immune response of the treatment can be evaluated. In other embodiments, an immune therapy can be applied after applying the histotripsy. In one embodiment, the lysed and solubilized cells can be extracted from the tissue. The extracted cells can be used to create immune therapies, including vaccines.