The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2023

Filed:

Feb. 06, 2019
Applicants:

The Johns Hopkins University, Baltimore, MD (US);

Duke University, Durham, NC (US);

Inventors:

Martin G. Pomper, Baltimore, MD (US);

Ronnie C. Mease, Fairfax, VA (US);

Vivek Kumar, Rensselaer, NY (US);

Sangeeta Ray, Ellicott City, MD (US);

Michael Zalutsky, Chapel Hill, NC (US);

Ganesan Vaidyanathan, Chapel Hill, NC (US);

Assignees:

The Johns Hopkins University, Baltimore, MD (US);

Duke University, Durham, NC (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0497 (2013.01); A61P 35/00 (2018.01);
Abstract

Small molecule radiohalogenated PSMA inhibitors and metal complexes thereof and their use in radioimaging and radiotherapy for treating PSMA-related diseases, including prostate cancer, are disclosed. The combination of small molecule radiohalogenated PSMA inhibitors with a competitive PSMA ligand for reducing off target accumulation of the radiohalogenated PSMA inhibitor also is disclosed.


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