The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2023

Filed:

Mar. 04, 2021
Applicant:

Theralase Technologies, Inc., Toronto, CA;

Inventors:

Arkady Mandel, North York, CA;

Roger Dumoulin-White, Toronto, CA;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61N 7/00 (2006.01); A61N 5/06 (2006.01); A61K 31/33 (2006.01); A61K 38/40 (2006.01); A61N 5/067 (2006.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0033 (2013.01); A61K 31/33 (2013.01); A61K 38/40 (2013.01); A61N 5/06 (2013.01); A61N 7/00 (2013.01); A61P 35/00 (2018.01); A61N 5/067 (2021.08); A61N 2007/0004 (2013.01);
Abstract

A method for destroying cells and/or microorganisms in an organism includes the following steps: (a) administering to the organism a composition including a sonosensitizing compound containing at least one transition metal with three bidentate ligands; and (b) exposing the sonosensitizing compound in the organism to ultrasound, wherein the ultrasound is effective to activate the sonosensitizing compound to destroy at least one of the cells and the microorganisms in the organism. The ultrasound is preferably used in conjunction with electromagnetic therapies comprising photodynamic therapy, low-level laser therapy, and radiation therapy. The ultrasound is preferably administered at a duty cycle in the range from 5% to 95% at a power density of 10 W/cmand a frequency in the range from 10 Hz to 10 MHz.


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