The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2023

Filed:

Oct. 03, 2019
Applicant:

Gusto Global, Llc, Charlotte, NC (US);

Inventors:

Daniel van der Lelie, Chapel Hill, NC (US);

Safiyh Taghavi, Chapel Hill, NC (US);

Assignee:

Gusto Global, LLC, Charlotte, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06G 7/48 (2006.01); G16B 5/00 (2019.01); A61K 35/741 (2015.01); A61K 35/742 (2015.01); G16B 35/20 (2019.01); G16B 35/00 (2019.01); G16B 99/00 (2019.01);
U.S. Cl.
CPC ...
G16B 5/00 (2019.02); A61K 35/741 (2013.01); A61K 35/742 (2013.01); G16B 35/00 (2019.02); G16B 35/20 (2019.02); G16B 99/00 (2019.02);
Abstract

Methods are provided for the rational design of stable communities of microbes for benefiting the health of a host organism, including human and/or animal health. The methods describe design of microbial consortia based on providing and/or complementing key functionalities lacking or underrepresented in the microbiome of an organism having a disorder or disease as compared to healthy subjects. The consortia are designed to possess metabolic interdependencies for improved engrafting, stability and performance of the consortium. Compositions that include the designed microbial consortia are provided for treatment of disorders/diseases involving chronic inflammation, infection, and the combination of chronic inflammation and infection including inflammatory bowel disease and related disorders. The compositions are also broadly applicable for the treatment of neurological, metabolic and oncology-related conditions.


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