The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2023

Filed:

Sep. 16, 2022
Applicant:

University of Washington Through Its Center for Commercialization, Seattle, WA (US);

Inventors:

Daniel T. Chiu, Seattle, WA (US);

Mengxia Zhao, Seattle, WA (US);

Wyatt Nelson, Seattle, WA (US);

Perry G. Schiro, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); B01L 3/00 (2006.01); G01N 15/06 (2006.01); G01N 15/14 (2006.01); G01N 33/49 (2006.01); G01N 21/64 (2006.01); G01N 33/53 (2006.01); G01N 35/10 (2006.01); G01N 35/00 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57492 (2013.01); B01L 3/502761 (2013.01); B01L 3/561 (2013.01); B01L 3/567 (2013.01); G01N 15/0612 (2013.01); G01N 15/0656 (2013.01); G01N 15/1456 (2013.01); G01N 15/1484 (2013.01); G01N 21/6428 (2013.01); G01N 21/6456 (2013.01); G01N 33/49 (2013.01); G01N 33/5304 (2013.01); B01L 3/502738 (2013.01); B01L 3/502776 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0883 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/06 (2013.01); B01L 2400/0633 (2013.01); B01L 2400/086 (2013.01); G01N 15/0618 (2013.01); G01N 35/0098 (2013.01); G01N 2015/0681 (2013.01); G01N 2015/0693 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/149 (2013.01); G01N 2035/00237 (2013.01); G01N 2035/00356 (2013.01); G01N 2035/1034 (2013.01);
Abstract

Provided herein, among other aspects, are methods and apparatuses for analyzing particles in a sample. In some aspects, the particles can be analytes, cells, nucleic acids, or proteins and contacted with a tag, partitioned into aliquots, detected by a ranking device, and isolated. The methods and apparatuses provided herein may include a microfluidic chip. In some aspects, the methods and apparatuses may be used to quantify rare particles in a sample, such as cancer cells and other rare cells for disease diagnosis, prognosis, or treatment.


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