The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2023

Filed:

Dec. 04, 2018
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

David Charles Schwartz, Madison, WI (US);

Subhrangshu Nandi, Madison, WI (US);

Michael Abbott Newton, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2022.01); G01N 21/64 (2006.01); G16B 30/00 (2019.01); C12Q 1/6818 (2018.01); G02B 21/16 (2006.01); G02B 21/36 (2006.01); G06V 20/69 (2022.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); C12Q 1/6818 (2013.01); G01N 21/6458 (2013.01); G02B 21/16 (2013.01); G02B 21/365 (2013.01); G06V 20/693 (2022.01); G06V 20/695 (2022.01); G06V 20/698 (2022.01); G16B 30/00 (2019.02); G01N 2021/6439 (2013.01); G06V 2201/03 (2022.01);
Abstract

Systems and methods for identifying sequence information from measurements made on single nucleic acid molecules are disclosed. The systems and methods can include binding portions of nucleic acid molecules with marker molecules, such as fluorescent molecules and/or intercalating molecules. The marker molecules provide a detectable signal that includes information about the underlying genomic information of the location on the nucleic acid molecule where a given marker molecule is bound. A profile of the detectable signal along a position of the nucleic acid is acquired for multiple different nucleic acid molecules. The PRIMR algorithm processes the data to provide a consensus profile from which a consensus underlying genomic information can be determined.


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