The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2023

Filed:

Jun. 04, 2020
Applicant:

Stokes Bio Ltd., Limerick, IE;

Inventors:

Mark Davies, Limerick, IE;

Tara Dalton, Limerick, IE;

Assignee:

STOKES BIO LTD., Limerick, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/686 (2018.01); G01N 35/08 (2006.01); B01F 25/10 (2022.01); B01F 33/30 (2022.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 35/10 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); B01F 25/10 (2022.01); B01F 33/30 (2022.01); B01L 3/50273 (2013.01); B01L 3/502776 (2013.01); B01L 3/502784 (2013.01); B01L 7/525 (2013.01); G01N 35/08 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/141 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/185 (2013.01); B01L 2400/0409 (2013.01); B01L 2400/0487 (2013.01); G01N 35/1095 (2013.01); G01N 2035/00514 (2013.01);
Abstract

A microfluidic analysis system () performs polymerase chain reaction (PCR) analysis on a bio sample. In a centrifuge () the sample is separated into DNA and RNA constituents. The vortex is created by opposing flow of a silicon oil primary carrier fluid effecting circulation by viscous drag. The bio sample exits the centrifuge enveloped in the primary carrier fluid. This is pumped by a flow controller () to a thermal stage (). The thermal stage () has a number of microfluidic devices () each having thermal zones () in which the bio sample is heated or cooled by heat conduction to/from a thermal carrier fluid and the primary carrier fluid. Thus, the carrier fluids envelope the sample, control its flowrate, and control its temperature without need for moving parts at the micro scale.


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