The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2023

Filed:

Jul. 14, 2020
Applicants:

Dignity Health, Phoenix, AZ (US);

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

Inventors:

Rachael Sirianni, San Francisco, CA (US);

Rebecca Cook, Scottsdale, AZ (US);

Tsafrir Mor, Tempe, AZ (US);

Joseph Blattman, Scottsdale, AZ (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/00 (2006.01); C07K 16/28 (2006.01); A61K 47/68 (2017.01); C12N 15/82 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); C12N 15/86 (2006.01); C12N 15/74 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 9/0019 (2013.01); A61K 47/6817 (2017.08); A61P 35/00 (2018.01); C07K 16/2809 (2013.01); C12N 15/743 (2013.01); C12N 15/8258 (2013.01); C12N 15/86 (2013.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C07K 2319/33 (2013.01); C07K 2319/55 (2013.01);
Abstract

Disclosed herein are compositions comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell. Also disclosed herein are methods of treating cancer in a subject, comprising: providing a composition comprising a polypeptide with at least two domains, wherein the first domain is capable of binding CD3 and the second domain is capable of binding to a cancer cell; and treating the cancer by administering a therapeutically effective dosage of the composition to the subject.


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