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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11807646 B1

PDFFull Text
Date of Patent:
Nov. 07, 2023

Filed:

Jan. 31, 2019

4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (usp19)

Applicant:

Almac Discovery Limited, Craigavon, GB;

Inventors:

James Samuel Shane Rountree, Craigavon, GB;

Steven Kristopher Whitehead, Craigavon, GB;

Adam Piotr Treder, Craigavon, GB;

Lauren Emma Proctor, Craigavon, GB;

Steven David Shepherd, Craigavon, GB;

Frank Burkamp, Craigavon, GB;

Joana Rita Castro Costa, Craigavon, GB;

Colin O'Dowd, Craigavon, GB;

Timothy Harrison, Craigavon, GB;

Assignee:

ALMAC DISCOVERY LIMITED, Craigavon, GB;

Attorneys:

Brian C. Trinque

Nicole Sassu

Lathrop GPM LLP

Primary Examiner:

Laura L Stockton

Int. Cl.
CPC ...
C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 498/04 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/06 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 491/107 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/06 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 491/107 (2013.01); C07D 495/04 (2013.01);
Abstract

Inhibitors of ubiquitin specific protease 19 (USP19) of Formula (I) are provided, together with pharmaceutical compositions comprising said inhibitors, and methods of use thereof. The compounds can be used in in the treatment of muscular atrophy, obesity, insulin resistance or type II diabetes or in reducing the loss of muscle mass.

Find Patent Forward Citations

Rountree, James Samuel Shane. (2023). 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (usp19) (U.S. Patent No. 11807646). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11807646

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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