The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2023

Filed:

Oct. 09, 2020
Applicant:

Chemocentryx, Inc., Mountain View, CA (US);

Inventors:

Pingchen Fan, Fremont, CA (US);

Rebecca M. Lui, Mountain View, CA (US);

Venkat Reddy Mali, Cupertino, CA (US);

Rajinder Singh, Belmont, CA (US);

Yibin Zeng, Foster City, CA (US);

Penglie Zhang, Foster City, CA (US);

Assignee:

CHEMOCENTRYX, INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/60 (2006.01); A61K 45/06 (2006.01); A61K 31/451 (2006.01);
U.S. Cl.
CPC ...
C07D 211/60 (2013.01); A61K 31/451 (2013.01); A61K 45/06 (2013.01); C07B 2200/05 (2013.01);
Abstract

Compounds are provided to modulate the C5a receptor. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, Rand Rare as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.


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