The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2023

Filed:

Jan. 31, 2022
Applicant:

New Jersey Institute of Technology, Newark, NJ (US);

Inventors:

Murat Guvendiren, Metuchen, NJ (US);

Shen Ji, Kearny, NJ (US);

Alperen Abaci, Harrison, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B33Y 10/00 (2015.01); A61L 27/52 (2006.01); A61L 27/50 (2006.01); A61L 27/56 (2006.01); A61L 27/20 (2006.01); A61L 27/38 (2006.01); B29C 64/106 (2017.01); B29C 64/40 (2017.01); B29L 31/00 (2006.01); B33Y 70/00 (2020.01); B29K 105/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/52 (2013.01); A61L 27/20 (2013.01); A61L 27/38 (2013.01); A61L 27/507 (2013.01); A61L 27/56 (2013.01); B29C 64/106 (2017.08); B29C 64/40 (2017.08); B33Y 10/00 (2014.12); A61L 2420/08 (2013.01); B29K 2105/0061 (2013.01); B29L 2031/753 (2013.01); B33Y 70/00 (2014.12);
Abstract

Disclosed is a new 3D bioprinting method of soft polymeric material such as a hydrogel or elastomer and/or cells for scaffolds or devices with structures. The method utilizes in one aspect extrusion based printing of polymer solutions, hydrogels and cells referred as direct ink writing (DIW) or BioPlotting that is modified to offer break-through advantages. The method may utilize sequential printing of a photocurable polymer solution or matrix material, and a functional hydrogel and/or cells. Printing within or inside of a viscous non-cured layer is accomplished by printing cells directly into the functional hydrogel. The viscous layer does not need to be shear thinning and thus allows use of a wide variety of bioinks never before allowed because of shear thinning and recovery requirement of commonly utilized extrusion based embedded bioprinting approach. Complex printing patterns never before allowed for bioinks are now possible utilizing this new printing method.


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