The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2023
Filed:
Oct. 11, 2022
Applicant:
4d Molecular Therapeutics Inc., Emeryville, CA (US);
Inventors:
David H. Kirn, Emeryville, CA (US);
Melissa Kotterman, Emeryville, CA (US);
Peter Francis, Emeryville, CA (US);
David Schaffer, Emeryville, CA (US);
Paul Szymanski, Emeryville, CA (US);
Kevin Whittlesey, Emeryville, CA (US);
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/40 (2006.01); A61K 9/00 (2006.01); A61P 3/00 (2006.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2465 (2013.01); A61K 9/0019 (2013.01); A61K 48/0066 (2013.01); A61K 48/0075 (2013.01); A61K 48/0083 (2013.01); A61P 3/00 (2018.01); C12N 15/86 (2013.01); C12Y 302/01022 (2013.01); A61K 48/00 (2013.01); C12N 2840/00 (2013.01);
Abstract
The present disclosure provides codon optimized nucleotide sequences encoding human alpha-galactosidase A, vectors, and host cells comprising codon optimized alpha-galactosidase A sequences, and methods of treating disorders such as Fabry disease comprising administering to the subject a codon optimized sequence encoding human alpha-galactosidase A.