The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2023
Filed:
Mar. 14, 2017
Methods of treating ocular inflammation and chemical injuries of the eye with extracellular vesicles
Capricor, Inc., Beverly Hills, CA (US);
Luis Rodriguez-Borlado, Manhattan Beach, CA (US);
Houman Hemmati, Los Angeles, CA (US);
Jennifer L Johnson, Van Nuys, CA (US);
Kiel A. Peck, West Hollywood, CA (US);
Rachel R. Smith, Cary, NC (US);
Linda Marban, Santa Monica, CA (US);
Capricor, Inc., San Diego, CA (US);
Abstract
The present invention relates to a method of treating a chemical injury of the eye, in particular alkali burn of the cornea, as well as ocular GVHD and similar inflammatory ocular conditions, with extracellular vesicles, in particular exosomes obtained from human cardiospheres or cardiosphere-derived cells. The present invention also provides a formulation comprising extracellular vesicles, in particular exosomes obtained from human cardiospheres or cardiosphere-derived cells, for subconjunctival or topical administration to the eye in the treatment of a chemical injury of the eye, in particular alkali burn of the cornea, as well as ocular GVHD and similar inflammatory ocular conditions.