The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2023
Filed:
Oct. 09, 2019
Applicant:
Duke University, Durham, NC (US);
Inventors:
Pei Zhou, Durham, NC (US);
Jiyong Hong, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4706 (2006.01); A61K 33/243 (2019.01); A61P 35/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4706 (2013.01); A61K 33/243 (2019.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01);
Abstract
This invention relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to translesion synthesis (TLS) pathway. More particularly, this disclosure relates to small molecule inhibitors of TLS, methods of inhibiting TLS pathway with these compounds, and methods of treating diseases related to the TLS pathway.