The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2023
Filed:
Mar. 05, 2021
Applicant:
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Inventors:
Navita Mallalieu, Montclair, NJ (US);
Ifeatu Egbuna, Hopkinton, MA (US);
Brian J. Hare, Arlington, MA (US);
Alexander Wolfgang Krug, Needham, MA (US);
Shu-Pei Wu, Cambridge, MA (US);
Assignee:
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61P 13/12 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 31/573 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 9/0053 (2013.01); A61K 9/2013 (2013.01); A61K 9/2054 (2013.01); A61K 31/573 (2013.01); A61K 45/06 (2013.01); A61P 13/12 (2018.01); C07B 2200/13 (2013.01);
Abstract
This application describes methods of inhibiting APOL1 and treating APOL1-mediated kidney diseases comprising administering Compound I and/or a pharmaceutically acceptable salt thereof. The application also describes pharmaceutical compositions comprising Compound I and/or a pharmaceutically acceptable salt thereof.