The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Apr. 18, 2022
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Olivia M. Viessmann, Cambridge, MA (US);

Jonathan R. Polimeni, Cambridge, MA (US);

Bruce Fischl, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/48 (2006.01); G01R 33/56 (2006.01); G06N 3/045 (2023.01);
U.S. Cl.
CPC ...
G01R 33/4806 (2013.01); G01R 33/5608 (2013.01); G06N 3/045 (2023.01);
Abstract

Anatomical, physiological, instrumental, and other related biases are removed from functional magnetic resonance imaging ('fMRI') signal data using deep learning algorithms and/or models, such as a neural network. Bias characterization data are used as an auxiliary input to the neural network. The bias characterization data can be subject-specific bias characterization data (e.g., cortical thickness maps, cortical orientation angle maps, vasculature maps), hardware-specific bias characterization data (e.g., coil sensitivity maps, coil transmission profiles), or both. The subject-specific bias characterization data can be extracted from the fMRI signal data using a second neural network. The bias-reduced fMRI signal data can include time-series signals, functional activation maps, functional connectivity maps, or combinations thereof.


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