The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2023
Filed:
Jul. 11, 2018
The Curators of the University of Missouri, Columbia, MO (US);
Shubhra Gangopadhyay, Columbia, MO (US);
Sangho Bok, Washington, UT (US);
Cherian Joseph Mathai, Columbia, MO (US);
Keshab Gangopadhyay, Columbia, MO (US);
Sheila Grant, Columbia, MO (US);
Aaron Wood, Tucson, AZ (US);
Syed Barizuddin, Columbia, MO (US);
The Curators of the University of Missouri, Columbia, MO (US);
Abstract
The invention broadly relates techniques for imaging and medical diagnosis and, more particularly, to the fabrication of flexible plasmonic gratings and the use thereof in detection of biomarkers. A first aspect of the invention provides for techniques for the fabrication of novel, flexible plasmonic gratings that can be inexpensively fabricated onto fiber optic cables, flexible films and substrates with non-uniform surfaces to enhance the imaging resolution. A second aspect of the invention provides for an ultra¬high sensitivity (single molecule counting) biomarker detection platform useable for medical diagnosis based on a fluorescent sandwich ELISA assay performed on a plasmonic grating platform incorporated with a fluorescence detection unit.