The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Sep. 12, 2017
Applicant:

Nanyang Technological University, Singapore, SG;

Inventors:

Bin Wu, Singapore, SG;

Renliang Yang, Singapore, SG;

Yee Hwa Wong, Singapore, SG;

Julien Lescar, Singapore, SG;

Chuan Fa Liu, Singapore, SG;

James P Tam, Singapore, SG;

Kien Truc Giang Nguyen, Singapore, SG;

Ziqi Long, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C12N 9/00 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 14/415 (2013.01); C12N 9/93 (2013.01);
Abstract

The present invention relates to a method of ligating a first peptide via its C-terminus to the N-terminus of a second peptide, wherein the reaction is catalyzed by an asparagine/aspartate (Asx) peptide ligase OaAEPI Cys247Ala having the amino acid sequence of SEQ ID NO: 1. Further encompassed are a method of preparing a dimer, oligomer, or multimer of one or more peptides of interest and a method of modifying or tagging the surface of a target cell by one or more peptides of interest. Also encompassed in the invention are the ligated peptides and/or tagged target cells obtainable according to any of the methods, the peptide ligase OaAEPI Cys247Ala having the amino acid sequence of SEQ ID NO: 1, as well as kits comprising said peptide ligase.


Find Patent Forward Citations

Wu, Bin. (2023). Methods for enzymatic peptide ligation (U.S. Patent No. 11795488). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11795488

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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