The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Oct. 30, 2017
Applicant:

Emendobio Inc., Wilmington, DE (US);

Inventors:

David Baram, Tel Aviv, IL;

Lior Izhar, Tel Aviv, IL;

Rafi Emmanuel, Ramla, IL;

Assignee:

EMENDOBIO, INC., Wilmington, DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); C12N 9/22 (2013.01); C12N 2310/20 (2017.05);
Abstract

The present invention relates to compositions and methods for increasing the rate of site specific insertion of a donor DNA sequence to the genome. More specifically, the method introduces a donor DNA template containing at least one transcription factor binding site to a cell in order to favor specific insertion of a donor template sequence at a target site by homology directed repair (HDR).


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