The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2023
Filed:
Oct. 15, 2018
Applicant:
Ursure, Inc., Boston, MA (US);
Inventors:
Giffin Daughtridge, Cambridge, MA (US);
Keith Kardos, Bethlehem, PA (US);
Assignee:
OraSure Technologies, Inc., Bethlehem, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); C07F 9/6561 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); A61K 47/646 (2017.08); C07F 9/65616 (2013.01); G01N 33/5308 (2013.01); G01N 33/543 (2013.01); G01N 33/54388 (2021.08); C07K 2317/565 (2013.01);
Abstract
The invention provides novel compounds, reagents, systems, and methods for detecting a metabolite related to a NRTI in a biological sample, and use thereof in monitoring adherence to pre-exposure prophylaxis or anti-retroviral treatment. Such reagents comprise NRTI derivatives, analogs, NRTI derivatives conjugates, along with antibodies directed to same, which are useful for anti-body-based methods, such as a lateral flow immunoassay and other point of care devices.