The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2023
Filed:
Feb. 19, 2020
Biontech Ag, Mainz, DE;
Ganymed Pharmaceuticals Gmbh, Mainz, DE;
Tron—translationale Onkologie an Der Universitätsmedizin Der Johannes Gutenberg-universität Mainz, Mainz, DE;
Ugur Sahin, Mainz, DE;
Ozlem Tureci, Mainz, DE;
Korden Walter, Mainz, DE;
Meike Wagner, Mainz, DE;
Maria Kreuzberg, Mainz, DE;
Sabine Hacker, Mainz, DE;
Stefan Jacobs, Mainz-Kastel, DE;
BioNTech AG, Mainz, DE;
Astellas Pharma Inc., Tokyo, JP;
TRON—Translationale Onkologie an der Universität, Mainz, DE;
Abstract
The present invention provides methods for diagnosis or treatment of cancer diseases involving cancer stem cells comprising targeting CLDN6. In particular, the present invention provides a method of determining cancer stem cells comprising detecting cells expressing CLDN6. Furthermore, the present invention provides a method of treating or preventing cancer comprising inhibiting and/or eliminating cancer stem cells by administering an antibody having the ability of binding to CLDN6 to a cancer patient.