The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Aug. 04, 2017
Applicant:

Stichting Vumc, Amsterdam, NL;

Inventors:
Assignee:

STICHTING VUMC, Amsterdam, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/47 (2006.01); A61P 35/00 (2006.01); C07K 14/245 (2006.01); C07K 14/78 (2006.01); C07K 16/18 (2006.01); C12N 15/62 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C07K 14/4748 (2013.01); A61K 39/0011 (2013.01); A61P 35/00 (2018.01); C07K 14/245 (2013.01); C07K 14/78 (2013.01); C07K 16/18 (2013.01); C12N 15/62 (2013.01); C12Q 1/6886 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/585 (2013.01); A61K 2039/6068 (2013.01); C07K 2319/21 (2013.01); C07K 2319/35 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01);
Abstract

The invention is in the field of medicine. More specifically, it is in the field of diagnosing tumor angiogenesis status and in the field of medical treatment of a subject who is suffering, suspected to suffer, or might suffer from a tumor in the future. In particular, the invention relates to a fusion polypeptide comprising a foreign antigen and a self antigen, wherein said foreign antigen consists of a polypeptide comprising an amino acid sequence of at least 12-15 amino acid residues, 12-24% of which residues are hydrophilic, bulky amino acid residues selected from the group consisting of histidine, glutamate, arginine, glutamine, aspartic acid and/or lysine.


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