The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Aug. 02, 2021
Applicant:

Crystal Pharmaceutical (Suzhou) Co., Ltd., Jiangsu, CN;

Inventors:

Minhua Chen, Suzhou, CN;

Jing Zhang, Jiangsu, CN;

Siming Zou, Suzhou, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/57 (2006.01);
U.S. Cl.
CPC ...
C07D 263/57 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure relates to novel crystalline forms of tafamidis (hereinafter referred to as compound I) and processes for preparation thereof. The present disclosure also relates to pharmaceutical composition containing the novel crystalline forms, use of the novel crystalline forms for preparing drugs treating disease caused by transthyretin-mediated amyloidosis. The crystalline forms of tafamidis of the present disclosure have one or more improved properties compared with crystalline forms of prior art and have significant value for future drug optimization and development.


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