The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Mar. 20, 2019
Applicant:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

David Issadore, Philadelphia, PA (US);

Melaku Muluneh Woldemariam, Philadelphia, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B81C 1/00 (2006.01); B81C 99/00 (2010.01); B01L 3/00 (2006.01); B01F 23/41 (2022.01); B01F 33/81 (2022.01); B01F 33/3011 (2022.01); B01F 35/10 (2022.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01F 23/41 (2022.01); B01F 33/3011 (2022.01); B01F 33/813 (2022.01); B01F 35/10 (2022.01); B01L 3/502707 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/0893 (2013.01);
Abstract

A microfluidic device contains a first layer having a plurality of channels, a second layer having a plurality of droplet makers, and a third layer having a plurality of through-holes connecting the plurality of channels to the plurality of droplet makers. The channels have a height of at least 4 times greater than the height of the droplet makers. The microfluidic device has at least 500 droplet makers in an area less than 10 cm. The channels are formed by direct laser-micromachining and the droplet makers are formed by soft lithography molding.


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