The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2023
Filed:
Sep. 05, 2018
Applicant:
University of Pittsburgh-of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Inventors:
Xucai Chen, Pittsburgh, PA (US);
Qin Bin, Pittsburgh, PA (US);
Villanueva Flordeliza, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 37/00 (2006.01); A61K 9/00 (2006.01); A61K 31/409 (2006.01); A61K 41/00 (2020.01);
U.S. Cl.
CPC ...
A61M 37/0092 (2013.01); A61K 9/0009 (2013.01); A61K 31/409 (2013.01); A61K 41/0047 (2013.01); A61M 2210/12 (2013.01);
Abstract
The systems and methods disclosed herein relate generally to microbubble-assisted delivery of a therapeutic agent, such as a chemotherapeutic agent, to cells or tissue of interest, either in vitro or in vivo, that can be activated by directed ultrasound irradiation. For example, hydrophobic sonosensitizers can be incorporated in microbubble complexes to provide improved sonodynamic therapies.