The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

May. 26, 2021
Applicants:

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Codagenix Inc., Farmingdale, NY (US);

Inventors:

Teresa B. De Los Santos, Miller Place, NY (US);

Aida E. Rieder, Westbrook, CT (US);

Fayna C. Diaz-San Segundo, Blue Point, NY (US);

Anna Kloc, Guilford, CT (US);

John R. Coleman, Blauvelt, NY (US);

Steffen Mueller, Kings Point, NY (US);

Gisselle N. Medina, Sound Beach, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/135 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/135 (2013.01); C12N 7/00 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/552 (2013.01); C12N 2770/32121 (2013.01); C12N 2770/32134 (2013.01);
Abstract

The present disclosure describes deoptimized foot and mouth viruses and their use for prophylactic and therapeutic treatment of mammalian subjects. The recombinant viruses provided herein include alterations in several genomic regions as well as Differentiating Infected from Vaccinated Animals (DIVA) markers.


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