The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2023
Filed:
Oct. 10, 2019
Applicant:
Serum Institute of India Pvt Ltd, Pune, IN;
Inventors:
Rajeev Mhalasakant Dhere, Pune, IN;
Sambhaji Shankar Pisal, Pune, IN;
Jagdish Kamalaji Zade, Pune, IN;
Rajendra Narayan Sabale, Pune, IN;
Hitesh Kumar Malviya, Pune, IN;
Sunil Mahor, Pune, IN;
Chetan Vilasrao Joshi, Pune, IN;
Assignee:
Serum Institute Of India Pvt Ltd., Maharashtra, IN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/13 (2006.01); A61K 39/04 (2006.01); A61K 39/08 (2006.01); A61K 39/102 (2006.01); A61K 39/39 (2006.01); C12N 7/00 (2006.01); A61K 39/02 (2006.01); A61K 39/05 (2006.01); A61K 39/29 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/13 (2013.01); A61K 39/05 (2013.01); A61K 39/08 (2013.01); A61K 39/099 (2013.01); A61K 39/102 (2013.01); A61K 39/292 (2013.01); A61K 39/39 (2013.01); C12N 7/00 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/70 (2013.01); C12N 2730/10034 (2013.01); C12N 2770/32634 (2013.01);
Abstract
The present invention is directed to improved methods of Enterovirus inactivation by formaldehyde in presence of tromethamine buffer resulting in maximum recovery of D-antigen. Subsequent adsorption of said sIPV on aluminium hydroxide provides significantly dose reduced sIPV compositions.