The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2023
Filed:
Apr. 24, 2020
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Upmc, Pittsburgh, PA (US);
John J. Pacella, Pittsburgh, PA (US);
Xucai Chen, Pittsburgh, PA (US);
Francois Tchi Ho Yu, Montreal, CA;
Thiruganesh Ramasamy, Pittsburgh, PA (US);
Stephen D'Auria, West View, PA (US);
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
UPMC, Pittsburgh, PA (US);
Abstract
Disclosed herein are embodiments of a functionalized microbubble designed for treating and/or preventing vascular obstructions, including microvascular obstructions. The functionalized microbubble embodiments comprise a microbubble that can be activated upon exposure to ultrasound and further that has a lipid-based shell that is attached to an exteriorly-attached therapeutically active agent, such as a thrombolytic agent. Also disclosed herein are embodiments of a method for making and using the functionalized microbubble embodiments.