The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Mar. 23, 2020
Applicant:

Op-t Llc, Denver, CO (US);

Inventors:

David Hal Wagner, Jr., Denver, CO (US);

Martin Glenn Yussman, Denver, CO (US);

Charles W. Henry, Denver, CO (US);

Gisela M. Vaitaitis, Centennial, CO (US);

Assignee:

OP-T LLC, Aurora, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/00 (2006.01); C07K 14/00 (2006.01); A61K 38/08 (2019.01); A61K 45/06 (2006.01); A61P 25/28 (2006.01); A61K 38/07 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 38/07 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01);
Abstract

Methods and materials for treating and preventing autoimmune diseases, in particular, multiple sclerosis (MS) including small peptides are capable of interacting with CD40, thereby altering and/or modulating the ability of CD40 to interact with CD154, which apparently affects inflammation; and/or the use of such peptides in reducing the inflammatory response, and in particular, the autoimmune inflammatory response; and/or the use of such short peptides to prevent or reverse autoimmune disease, and particularly, multiple sclerosis, in individuals; and/or methods and materials for detecting T-cells that express CD40 (Th40 cells). Also provided are kits for reducing inflammation, treating autoimmune diseases, or detecting Th40 cells. Additionally, methods and apparatuses to administer the peptide are provided.


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