The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Apr. 09, 2021
Applicant:

Heptares Therapeutics Limited, Cambridge, GB;

Inventors:

Miles Stuart Congreve, Cambridge, GB;

Giles Albert Brown, Cambridge, GB;

Julie Elaine Cansfield, Cambridge, GB;

Benjamin Gerald Tehan, Cambridge, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); C07D 401/04 (2006.01); C07D 211/06 (2006.01); C07D 401/14 (2006.01); A61K 31/4545 (2006.01);
U.S. Cl.
CPC ...
A61K 31/55 (2013.01); A61K 31/4545 (2013.01); C07D 211/06 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01);
Abstract

This invention relates to compounds that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula I, where n is 1 or 2; p is 0, 1 or 2; q is 0, 1 or 2; and R-Rare as defined herein.


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